摘要
目的研究马齿苋的化学成分。方法利用硅胶、Sephadex-LH-20、ODS等柱色谱方法进行分离纯化,根据理化性质及波谱数据(1H-NMR、13C-NMR)进行结构鉴定。结果从马齿苋中分离得到8个化合物,分别鉴定为2,5-二羧基吡咯(1 H-pyrrole-2,5-dicarboxylic acid,1)、5-羟基-2-羧基吡啶(5-hydroxy-2-pyridinecarboxylic acid,2)、马齿苋酰胺B(oleracein B,3)、3,4-二羟基苯甲酸(3,4-di-hydroxybenzoic acid,4)、木栓酮(friedelin,5)、4α-甲基-3β-羟基-木栓烷(4α-methyl-3β-hydroxyl-friedelan,6)、羽扇豆醇(lupeol,7)、环(亮氨酸-苯丙氨酸)(cyclo(L-leucinyl-L-tyrosinyl),8)。结论化合物1、2、8首次从马齿苋属中分离得到。
Objective To separate and identify the chemical constituents of the extract from the Portulaca oleracea L. Methods The compounds were separated by repeated silica gel SephadexLH-20 and ODS. The structures of these isolated compounds were identified by analysis of their spectral data (1H-NMR, 13C-NMR) and chemical properties. Results Eight compounds were isolated from Portulaca oleracea L. and their structures were identified as 1H-pyrrole-2,5-dicarboxylic acid( 1 ) ,5-hydroxy-2-pyridinecarboxylic acid ( 2 ), oleracein B ( 3 ), 3,4-dihydroxybenzoic acid ( 4 ), friedelin ( 5 ), 4α-methyl-3β-hydroxylfriedelan ( 6 ), lupeol (7)and cyclo (L-leucinyl-L-tyrosinyl) (8). Conclusions Compounds 1,2 and 8 are isolated from Portulaca for the ftrst time.
出处
《沈阳药科大学学报》
CAS
CSCD
北大核心
2009年第11期878-881,共4页
Journal of Shenyang Pharmaceutical University
关键词
马齿苋
化学成分
结构鉴定
2
5-二羧基吡咯
5-羟基-2-羧基吡啶
环(亮氨酸-苯丙氨酸)
Portulaca oleracea L.
chemical constituent
structural identification
IH-pyrrole-2,5-dicarboxylic acid
5-hydroxy-2-pyridinecarboxylic acid
cycle(L-leucinyl-L-tyrosinyl)