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SDF-1／CXCR4在急性白血病中的研究进展 被引量：1

Progress of SDF-1/CXCR4 in acute leukemia
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摘要 基质细胞衍生因子-1（SDF-1）及其受体CXCR4相互作用传导特定信号，在许多生理和病理过程中发挥重要效应。CXCP4在急性白血病中高表达，与疾病的预后、耐药、复发密切相关。采用生物学策略治疗肿瘤，为治疗急性白血病开辟了新途径。
作者 王艳(综述) 刘晓日(综述) 殷小成(审校)
机构地区 南华大学附属第一医院儿科 南华大学附属南华医院儿科
出处 《国际儿科学杂志》 2009年第6期577-579,共3页 International Journal of Pediatrics
基金 衡阳市2007年科学技术发展计划项目（2007KS35）
关键词 基质细胞衍生因子-1 CXCP4 急性白血病
分类号 R730-36 [医药卫生—肿瘤] R733.71 [医药卫生—肿瘤]
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参考文献27

  • 1Bradstock KF, Makrynikola V, Bianchi A, et al. Effects of the the chemokine stromol-derived factor-1 on the migration and localization of precursor-B acute lymphoblastic leukemia cells within bone marrow stromol layers. Leukemia, 2000,14(5) :882-888.
  • 2Shen W, Bendall LJ, Gottlieb DJ, et al. The chemokine receptor CXCR4 entegrin-mediated in vitro adhesion and facilitates engraftment of leukemic precursor-B cells in the bone marrow. Exp Hematol, 2001,29(12) : 1439- 1447.
  • 3Spiegel A, Kollet O, Peled A, et al. Unique SDF-1-induced activation of human precursor-B ALL cells as a result of altered CXCR4 expression and signaling. Blood,2004,103(8) :2900-2907.
  • 4刘峥嵘,孙慧,张秋堂.CXCR4在急性B淋巴细胞白血病的表达及其意义[J].中国实验血液学杂志,2004,12(4):441-444. 被引量：5
  • 5曾东风,孔佩艳,陈幸华,彭贤贵,魏立,常诚,刘林,刘红,王庆余.SDF-1及其受体CXCR4在急性白血病与淋巴瘤表达的初步研究[J].中国实验血液学杂志,2005,13(2):274-277. 被引量：29
  • 6Crazzolara R, Kreczy A, Mann G, et al. High expression of the chemokine receptor CXCR4predicts extram edullary organ infiltration in in childhood acute lymphoblastic leukemia. Br J Haematol, 2001,115 (3) : 545-553.
  • 7Mohle R, Schittenhelm M, Failenschmid C, et al. Functional response of leukeamic blasts to stromal cell-drrived factor-1 correlates with preferential expression of the chemokine receptor CXCR4 in acute myelomonccytic and lymphoblastic leukaemia. Br J Haematol, 2000,110(3) : 563-572.
  • 8Wang JF, Liu ZY, Groopman JE. The alpha-chemokine receptor CXCR4 is expressed on the megakaryocytic lineage from progenitor to platelets and modulates migration and adhesion. Blood, 1998,92(3) : 756-764.
  • 9Voemans C, van Heese WP, de Jong I, et al. Migratory behavior leukemic cell from acute myeloid leukemia patients. Leukemia, 2002, 16 (4) : 650- 657.
  • 10Kalinkovich A, Tavor S, Avigdor A, et al. Functional CXCR4-expressing microparticles and SDF-1 correlate with circulating acute myelogenous leukemia cell. Cancer Res, 2006,66(22) : 11013-11020.

二级参考文献27

  • 1Mohle R, Schittenhelm M, Failenschmid C, et al. Functional response of leukemic blasts to stromal cell-derived factor-1 correlates with preferential expression of the chemokine receptor CXCR4 in acute myelomonocytic and lymphoblastic leukemia. Br J Haemat
  • 2Broxcymeyer HE, Kohli L, Kim CH. et al. Stromal cell-derived factor-1/CXCL12, directely enhances survival/antiapoptosis of myeloid progenitor cell through CXCR4 and G (alpha) proteins and enhances engraftment of competitive; repopulating stem cells. J Leu
  • 3Baruchel A, Cayuela JM, Ballerini P, et al. The majority of myeloid-antigen-positive(My+ ) childhood B-cell precursor acute lymphoblastic leukaemias express TEL-AML1 fusion transcripts. Br J.Haematol, 1997; 99: 101- 106
  • 4Gattei V, Aldinucci D, Attadia V, et al. Human granulocyte-macrophage colony-stimulating factor supports the clonogenic growth of B-lineage acute lymphoblastic leukaemia expressiing myeloid antigens. Cytokine Cell Mol Ther, 1997; 3:141 - 151
  • 5Mohle R, Bautz F, Rafil S. et al. The chemokine receptor CXCR4 is expressed on CD34+ heamotopoitic progenitors and leukemic cell mediates transendothelial migration induced by sromal cell-derived factor- 1. Blood, 1998; 91: 4523 - 4530
  • 6Ishii T, Nishihara M, Ma F, et al. Expression of stromal cell-derived factor-1/Pre-B cell growth-stimulating factor receptor, CXC chemokine receptor 4 on CD34 + human bone marrow cells is a phenotypic alteration for committed lymphoid progenitors. J Immun
  • 7Crazzdara R, Krecy A, Mann A, et al. High expression of chemockine receptor CXCR4 predicts extramedullary organ infiltration in chilhood acute lymphoblastic leukaemia. Br J Haematol, 2001;115: 545 - 533
  • 8Weir EG, Borowits MJ. Flow cytometry in the diagnosis of acute leukemia. Semin Hematol, 2001; 38:124 - 138
  • 9Huh YO, Ibrahim S. Immunophenotypes in adult acute lymphocytic leukemia. Role of flow cytometry in diagnosis and monitoring of diseases. Hematol Oncol Clin North Am. 2000; 14:1251 - 1265
  • 10Jennings CD. Foon KA. Recent advances in flow cytometry: application to the diagnosis of hemotologic maligency. Blood, 1997; 90:2863 - 2892

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国际儿科学杂志
2009年 第6期

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