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水通道蛋白4与脑水肿的关系 被引量:1

The relationship of aquaporin-4 and brain edema
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摘要 水通道蛋白(AQP)是近年来发现的在水分子跨膜流动方面起着关键作用的一种细胞膜通道蛋白。AQP4是一种主要在大脑内表达的AQP,主要分布于脑实质和室管膜周的星形胶质足突上,这种分布表明AQP4参与了进出脑实质内水的调节。肝性脑病、脑缺血、脑肿瘤、颅内感染、脑外伤等均可导致脑水肿。目前对其治疗方法非常局限,AQP4的发现可能对脑水肿的治疗提供新的靶点。
出处 《国际儿科学杂志》 2009年第6期592-594,共3页 International Journal of Pediatrics
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