摘要
细菌回复突变试验(Ames试验)被广泛应用于药物、化学品及医疗器械产品等的遗传毒性研究中。具备完整的背景数据是Ames试验规范化的必要内容,也是验证试验系统正确性和获取数据可靠性的保证。本文介绍了细菌回复突变试验背景数据的采集方法。
Bacterial reverse mutation test(Ames test) is widely used in genetic toxicology research for products such as drugs,chemicals and medical equipments.A complete set of historical data is required for standardizing the Ames test,and for assuring the correctness of the experimental system and the reliability of the data obtained.This article introduced a method in collecting historical data for bacterial reverse mutation test,which can be used as a reference.
出处
《中国新药杂志》
CAS
CSCD
北大核心
2009年第22期2110-2112,共3页
Chinese Journal of New Drugs
基金
国家科技支撑计划课题(2006BAI141306)
关键词
细菌回复突变试验
背景数据
采集
bacterial reverse mutation test
historical data
collection