HSP70s CD_(68)在类风湿关节炎滑膜组织中的表达研究

The expression of HSP70s、CD68 in Rheumatoid arthritis synovial tissue

目的了解HSP70s、CD68在滑膜组织中的表达分布情况。方法采用免疫组化SP法对39例类风湿关节炎滑膜病理活检组织进行HSP70s和CD68染色。结果HSP70s、CD68在类风湿关节炎滑膜组织中均高度表达,滑膜组织增生明显则表达愈明显。结论HSP70s、CD68与类风湿关节炎的发病有关。

Objective To investigate the expression and distribution of HSP70s and CD68 in synovialis tissues. Methods HSP70s and CD68 of 39 synovial biopsy tissues with rheumatoid arthritis were determined by immunohistochemcal SP method. Results HSP70s and CD68 both highly expressed in synovialis tissues with rheumatoid arthritis. While synovialis tissues proliferated significantly, the more obviously HSP70s and CD68 expressed.Conclusion HSP70s and CD68 are associated with pathogenesis of rheumatoid arthritis.