呼出气冷凝液中pH测定的影响因素及pH检测的临床意义

Influential factors and clinical significance of pH in exhaled breath condensate

呼出气冷凝液检测技术为一项新型的呼吸道炎症状态检测方法。近年来国外对其研究进展很快，临床应用得到了很大发展，而其中以pH值检测技术应用最为广泛，目前广泛应用于哮喘、慢性阻塞性肺疾病、睡眠呼吸暂停综合征、肺癌、肺间质纤维化、结核、支气管扩张、囊性纤维化等多种呼吸系统疾病。本文把握国外相关研究的最新进展，重点综述了呼出气冷凝液标本收集、贮存、检测等环节对pH值的影响因素及其在常见呼吸系统疾病中的临床应用。

The technique of exhaled breath condensate is a new detective means for respiratory tract inflammation. It is more and more extensively applied in clinic because of the quick study abroad recently. However, the detective technique of pH is the most extensive one in exhaled breath condensate, and it is widely applied for asthma, chronic obstructive puhnonary disease, sleep apnea syndrome, lung cancer, pulmonary interstitial fibrosis, tuberculosis, bronchieetasis, cystic fibrosis and others. This article grasps the latest progress of relative study,reviews the influential factors of pH in exhaled breath condensate, including specimen collection, storage and detection, and the clinical application in the common diseases of respiratory system.