药物抑制气道支架植入后肉芽组织增生的研究进展

Progress of drugs in inhibiting exuberant granulation tissue after airway stent insertion

气道支架植入后肉芽组织增生导致再狭窄是影响其临床疗效的一大问题。药物涂层支架在抑制冠脉再狭窄领域做出了卓越贡献。因此，研究气道药物涂层支架是解决这一问题的尝试性探索。通过概述抑制气道支架植入后肉芽组织增生的各类药物，可以为进一步研制气道涂层支架的药物选择提供方向。

Airway stent-insertion restenosis caused by the exuberant granulation tissue is an important problem,which affects therapeutic effect in clinic. The drug eluting stent（DES） has played an important role in restraining the stent-insertion restenosis of coronary artery. Therefore, investigating airway DES to resolve the similar problem is an attempt. This paper reviews drugs which inhibit the exuberant granulation tissue after airway stent insertion, and provides direction for the development of airway DES.