瑞芬太尼复合依托咪脂用于无痛人工流产术的临床观察

An Clinical Observation of Remifentanil and Etomidate Used Jointly in Anesthesia for Induced Abortion

目的:比较芬太尼复合依托咪脂和瑞芬太尼复合依托咪脂用于无痛人工流产术的作用。方法:将80例早孕妇女随机分为两组,分别用芬太尼1.5μg/kg复合依托咪脂0.3 mg/kg(A组)和瑞芬太尼1.5μg/kg复合依托咪脂0.3 mg/kg(B组)诱导,术中病人躁动时添加依托咪脂0.1 mg/kg。监测术中心率、血压,记录手术时间、依托咪脂总用量、苏醒时间、离开手术室时间。结果:两组术中生命体征、依托咪脂用量、手术时间无显著差异。B组苏醒时间和离开手术室时间明显短于A组。结论:在无痛人流手术中,瑞芬太尼复合依托咪脂较芬太尼复合依托咪脂利于病人苏醒,缩短病人离开手术室时间。

Objective： To compare anesthetic action of fentanyl and etomidate and remifentanil together with etomidate, used for induced abortion. Methods： 80 cases of pregnancy for induced abortion were divided randomly into fentanyl and etomidate group（Group A） and remifentanil and etomidate group（Group B）. The patients from Group A were given fentanyl（1.5 μg/kg） and etomidate（0. 3 mg/kg） for induced abortion. Those from Group B were given remifentanil （1.5 μg/kg） and etomidate（0.3 mg/kg） for induced abortion, with 0.1 mg/kg etomidate additionally given if the patient remained restless. Heart rate and blood pressure were monitored in the course of operation and operation time, total consumption of etomidate, exact time for coming to themselves and duration at operation--room were taken down in detail. Results： There was no significant difference between the two groups in intraoperative vital signs, total consumption of etomidate and operation time. Time for coming to themselves and duration in the operation room in group B were shorter than that in group A（ P 〈0.05）. Conclusion： Jointly administration of remifentanil and etimidate for painless induced abortion can play a more effective role in helping the patients to come to themselves and in shortening duration at the operation- room in the course of operation.