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原发性腹膜癌综合治疗模式探讨

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摘要 目的探讨原发性腹膜癌综合治疗模式。方法对15例原发性腹膜癌患者采用术前静脉化疗加腹腔灌注化疗3~4周期,续肿瘤细胞减灭术,术后静脉化疗3~4周期的"三明治"模式综合治疗。结果15例患者经3~4周期术前腹腔灌注,13例腹水消失,获得手术机会(占86.6%)。近期疗效:总有效率RR 86.6%(13/15),CR 26.6%(4/15),PR 60.0%(9/15);SD 6.6%(1/15),PD 6.6%(1/15)。远期疗效:疾病进展时间平均18.6个月(16~21个月);平均生存期29个月(3~38个月)。结论采用术前腹腔灌注化疗为主+手术+术后静脉化疗为主的"三明治"治疗模式,近期疗效好;远期疗效与国内外文献报道接近,但因例数少、时间短尚无法准确评定。该治疗模式是否可以作为原发性腹膜癌的规范治疗模式值得进一步观察。
出处 《徐州医学院学报》 CAS 2009年第11期769-770,共2页 Acta Academiae Medicinae Xuzhou
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