干扰素联合伐昔洛韦治疗带状疱疹的临床效果及护理实践

Clinical effect and nursing observation of recombinant human interferonα-2b combined with acyclovir on treating herpes zoster

目的:探讨干扰素联合伐昔洛韦治疗带状疱疹的临床疗效。方法:将带状疱疹病人129例分成3组,治疗组口服伐昔洛韦片300 mg,每日2次,外涂干扰素乳膏,每日4次,配合适当的护理措施;对照Ⅰ组仅口服伐昔洛韦片,对照Ⅱ组仅外涂干扰素乳膏,观察3组病人的止痛、结痂、脱痂、治愈等情况。结果:治疗组疗效与各对照组比较差异有显著性(P<0.01),止痛、结痂、脱痂时间明显短于各对照组(P<0.01)。结论:干扰素联合伐昔洛韦并配合护理措施治疗带状疱疹明显提高疗效,减少后遗神经痛的发生率。

Objective：To determine the clinical curative effect of recombinate human interferon and valaciclovir on treating herpes zoster.nethods：The patients were divided into two groups.In the treatment group,300 mg valaciclovir tablets were orally taken,twice a day,and the recombinant human interferon cream was embrocated on the affected parts,4 times a day,with some proper nursing practice. In the control group Ⅰ ,the patients only took acyclovir tablets. In the control group Ⅱ ,the patients were only embrocated with the recombinant human interferon cream.To observe the condition of pain relieving,incrustation, decrustation, curing,etc.in the three groups.Results：The cure effect of the treatment group was better than that of the control groups,and the time of pain relieving,inerustation,decrustation were also shorter than those of the control groups,P〈0.01.Conclusion：The treatment of recombinant human interferon combined with valaciclovir on treating herpes zoster is more effective, and can reduce the incidence of residual nerval pain.