3FASS R J,BARHISHAN J,AYERD L W,et al. Emergence bacterial to imipenem and ciprofloxcin in an university hospital [ J ]. J Antimicrob Chemother, 1995,36 (2) :343 - 353.
2Heydom A,Ersboll B,Kato J,et al.Statistical analysis of Pseudomonas aeruginosa biofilm development:impact of mutations in genes involved in twitching motility,cell-to-cell signaling,and stationary-phase sigma factor expression [J].Appl Envir Microbiol,200
3Bagge N,Ciofu O,Hentzer M,et al.Constitutive high expression of chromosomal β-Lactamase in Pseudomonas aeruginosa caused by a new insertion sequence located in ampD [J] Antimicrob Agents Chemother ,2002,46 (11):3406
4Mac Gowan AP,Bowker KE.Mechanism of fluoroquinolone resistance is an important factor in determining the antimicrobial effect of gemifloxacin against Streptococcus pneumoniae in an in vitro pharrnacokinetic model [J].Antimicrob Agents Chemother ,2003,47 (
5Kureishi A,Diver JM,Beckthold B,et al.Cloning and nucleotide sequence of Pseudomonas aeruginosa gyrA gene from strain PAO1 and quinolone-resistant clinical isolates [J].Antimicrob Agents Chemother ,1994,38 (9):1944
6Takenouchi T,Sakagawa E,Sugawara M.Detection of gyrA mutations among 335 Pseudomonas aeruginosa stains isolated in Japan and their susceptibilities to fluoroquinolones[J].Antimicrob Agents Chemother ,1999,43(2) :406
7Stove CK,Pham QX,Erwin AL,et al.Complete genome sequence of Pseudomonas aeruginosa PAO1 an opportunistic pathogen [J].Nature,2000,406:959
8Poole K.Efflux-mediated resistance to fluoroquinolones in gram-negative bacteria [J].Antimicrob Agents Chemother,2000,44 (9):2233
9Masuda N,Ohya S.Cross-resistance to meropenem,cephems,and quinolones in Pseudomonas aeruginosa [J].Antimicrob Agents Chemother ,1992,36(9) :1847
10Wong KK,Brinkman FS,Benz RS,et al.Evaluation of structural model of outer membrane protein OprM,an efflux component involved in intrinsic antibiotic resistance[J].J Bacteriol,2001,183(1) :367
