摘要
为探讨皮下注射速避凝对慢性肺心病急性期的疗效，于治疗前后同步检测２０例患者的纤维蛋白降解产物（ＦＤＰ，Ｄ－二聚体），抗凝血酶原Ⅲ（ＡＴ－Ⅲ），动脉血氧分压（ＰａＯ２）及动脉血二氧化碳分压（Ｐａ－ＣＯ２）。结果示：治疗组ＦＤＰ和Ｄ－二聚体治疗后较治疗前显著降低（Ｐ＜０．０１），ＡＴ－Ⅲ则显著升高（Ｐ＜０．０１），血气参数显著改善（Ｐ＜０．０１）；对照组（未用速避凝）治疗前后的各项检测指标差异均无显著性（Ｐ＞０．０５）。
Objective: The effects of fraxiparine with hypodermic on the treatment of patients with chronic pulmonary heart diseases(CPHD) at acute phase were studied. Methods: Twenty patients were hypodermically injected with 0.4 ml fraxiparine per day for 7 days as a course. Fibrin fibrinogen degradation products (FDP and D dimer), antithrombin Ⅲ (AT Ⅲ), PaO 2 and PaCO 2 were detected before and after the treatment. Results: In the therapy group, FDP and D dimer decreased after the treatment, AT Ⅲ increased. All indexes didn't alter in the control group. Conclusion: Fraxiparine is effective on patients with CPHD at acute phase.
出处
《湖南医科大学学报》
CSCD
1998年第5期470-472,共3页
Bulletin of Hunan Medical University
关键词
慢性
肺心病
速避凝
药物疗法
pulmonary heart disease
fibrin fibrinogen degeradation products
antithrombin
therapeutical use
