冠状动脉球囊成形术中反复血流阻断与缺血预适应现象的观察
摘要
为评价经皮穿刺冠状动脉球囊成形术（ＰＴＣＡ）中短时、反复的血流阻断－再灌是否具有抗急性缺血适应现象及缺血相关性心律失常的作用，连续观察了１３８例住院接受ＰＴＣＡ术冠心病患者的术前及术中心电图、心率和血压等变化。结果显示：①３８例患者术中出现室性早搏（ＶＥ），占总例数２７％，其中３０例于首次球囊扩张时发生了ＶＥ，９例记录到二联律或成对ＶＥ；另８例于再次球囊扩张时出现ＶＥ，无１例成对ＶＥ。前者的ＶＥ检出率显著高于后者（２２％ＶＳ５８％，Ｐ＜００１）；②出现ＶＥ的３８例患者的冠脉狭窄程度轻于其余无ＶＥ出现者（７４±１１％ＶＳ．８７±１２％，Ｐ＜００５）。提示：①短时反复的冠脉闭塞－再灌过程可减轻缺血心肌细胞的电不稳定性；②首次扩张后血流再灌的心肌对急性缺血产生较强的适应现象。
出处
《中国实用内科杂志》
CAS
CSCD
北大核心
1998年第11期662-663,共2页
Chinese Journal of Practical Internal Medicine
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