糖尿病并发尿路感染相关因素分析

Analysis of related factors on urinary tract infection with diabetes

目的探讨糖尿病并发尿路感染的相关因素。方法回顾性分析350例糖尿病患者临床资料。结果350例糖尿病患者中，并发尿路感染73例，占20．9％，女性186例患者中尿路感染者54例（29．0％），高于男性糖尿病患者164例中尿路感染者19例（11．6％）（X^2=16．08，P〈0．01）；空腹血糖〈11．1mmol／L，尿路感染者31例（17．4％），空腹血糖≥11．1mmol／L，尿路感染者42例（24．4％），餐后2h血糖〈16．7mmol／L，尿路感染者28例（15．4％），餐后2h血糖≥16．7mmol／L，尿路感染者45例（26．8％），血糖越高，尿路感染的发生率也越高（X^2=2．60、6．88，P〈0．01）；病程≥5年的糖尿病患者183例中并发尿路感染者48例（26．2％），高于病程〈5年的糖尿病患者167例中并发尿路感染者25例（15．0％）（X^2=6．70，P〈0．01）；尿培养显示致病菌以革兰阴性菌为主，占84．9％（62／73），主要为大肠埃希菌，占59．7％（37／62），其次为粪肠球菌，占11．2％（7／62），另还有阴沟杆菌、表皮葡萄球菌、克雷伯杆菌、产气杆菌、变形杆菌、白色念珠菌等。结论糖尿病并发尿路感染多见于女性、病程长、血糖高患者。

Objective To analyze the related factors of urinary tract infection with diabetes. Methods Retrespective studies were conducted in 350 diabetes cases who were in hospital from 2008.01.01 to 2008.12.31 in endocrine department of our hospital. Results The primary pathogen was Gram-negative bacteria（ 84. 9% ） ,The major one was Escherlchia coli （ 59. 7% ） , the followed one was Enterococcus faeealis （ 11.2% ）. The Bacillus cloacae. Staphylococcus epidemidis, Klebsiella pneumoniae, Bacillus aerogenes, Bacillus proteus, Blastomyces albicans also were the pathogens which caused the urinary tract infection. The influence of infection ： the higher was the incidence of female patients; The older was the diabetes patients, the higher was the incidence of urinary tract infection; The longer course of diabetes,the higher was the incidence of urinary tract infection; Complicated by the ketesis patients were higher in the incidence of urinary tract infection;The hyperglycosemia patients were higher than the multisystem patients;the patients with nervous bladder were higher than the patients without. Conclusion Diabetes patients who suffered from urinary tract infection are more in old lady,long course,hyperglycosemia and with urgent or chronicity complication.