254例医源性早产分析

Analysis of 254 Cases of Iatrogenic Preterm Labor

目的：分析研究医源性早产有关的危险因素及早产儿发病及死亡的相关因素。方法：回顾分析2002年1月～2008年12月我院254例医源性早产的原因，与603例自然早产相比分娩方式和新生儿窒息的差异。比较28～31^＋6周，32—34^＋6周和35．36^＋6周孕龄新生儿窒息和新生儿死亡的差异。结果：妊娠期高血压疾病，妊娠期肝内胆汁淤积症、前置胎盘，胎儿窘迫为引起医源性早产的最常见原因。医源性早产与自然早产组分娩方式和新生儿窒息发生率有显著性差异（P〈0．05）。结论：医源性早产与孕期多种因素有关，早产是围产儿发病和死亡的主要原因，重视早产的临床相关因素，降低围生儿并发症及死亡率。

To analyse and study the dangerous factors associated with iatrogenic premature labor and the etiology and reason of death inpremature infant. Methods ： The causes of 254 cases of iatrogenic preterm labor from January 2002 to December 2008 in my hospital were analyzed retrospectively and 603 controls at spontaneous premature labor group the delivery mode and neonatal asphyxia were compared. Compared of neonatal asphyxia and neonatal death rate in patients at 28-31^＋6 weeks gestation,B2 -34^＋6weeks gestation and 35 -36^＋6 weeks gestation. Results： The most common causes of iatrogenic preterm delivery were hypertensive disorder complicating pregnancy, intrahepatie cholestasis of pregnancy, placenta praevia and fetal distress, significant differnces was shown in the delivery mode and neonatal asphyxia rate between the two groups（ P 〈0.05 ）. Conclusion ：There are many factor lead to iatrogenic premature labor during gestational period, premature labor is main reason of disease and death in infant. Controling the factor caused premature labor in clinic and decreasing the complication and mortality in infant.