摘要
目的：了解幽门螺杆菌感染与血清胃泌素及生长抑素变化的关系。方法：采用ＲＩＡ法检测１２８例门诊行胃镜检查患者血清胃泌素、生长抑素浓度；同时以ＣＬＯ、ＥＬＩＳＡ法检查患者是否存在幽门螺杆菌感染。结果：幽门螺杆菌感染阳性患者血清胃泌素水平明显高于未感染者；而生长抑素水平则无差异。结论：幽门螺杆菌引起血清胃泌素增高进而造成胃酸分泌增多。
Objective: To investigate the relationship between serum gastrin (GAS) and somatostatin (SS) and Helicobacter pylori (Hp) infection. Methods: We detected serum GAS and SS by RIA, and serum Hp IgG antibody by ELISA in 128 endoscopy patients. Results: The serum GAS level [(83.37±28.39)pg/ml] in Hp positive patients was higher than that [(69.70±18.17)pg/ml] in Hp negative (P<0.05), but SS had no change. Conclusion: High gastrin caused by Hp infection leading to more gastric acid may be one of the pathogeneses of Hp infection.
出处
《第二军医大学学报》
CAS
CSCD
北大核心
1998年第5期479-480,共2页
Academic Journal of Second Military Medical University
关键词
幽门螺杆菌
胃泌素
生长抑素
elicobacter pylori
gastrin
somatostatin
