摘要
目的观察川崎病(KD)患儿血清降钙素原(PCT)水平的变化及其临床意义。方法30例KD(KD组)患儿静脉应用丙种球蛋白(IVIG)治疗。治疗前后,采用双抗夹心免疫发光法,使用全自动生化分析仪测定KD组血清PCT水平。并与30例对照组检测结果进行对比分析。结果KD组治疗前血清PCT水平明显高于治疗后(P<0.01);KD组治疗前血清PCT水平明显高于对照组(P<0.01)。结论KD患儿血清PCT明显升高,IVIG治疗后PCT明显下降,对其检测有助于KD的诊断和病情评价。
Objective To Observe the change of serum procalcitionin（PCT） level in kawasaki disease （KD） children patients and its clinical significance. Methods 30 KD（KD group） children patients were treated with immune globulin（IVIG） intravenously. The level of serum PCT were detected with double antibody sandwich immunoluminescence assay and the use of full-automatic biochemical analyzer before and after treatment. Meanwhile,the PCT of 30 healthy children （control group） were also detected. The results derived from the two groups were subjected to comparative analysis. Results The ante-treatment serum PCT in KD group was significantly higher than both post-treatment serum PCT level （P〈0.01） in PCT group and the PCT level in the control group（P〈0.01）. Conclusion The serum PCT level of KD children patients elevates significantly,and conspicuously decreases after being treated with IVIG,which indicates that the detection of serum PCT is a helpful in diagnosing KD and evaluating its condition.
出处
《江西医学院学报》
2009年第8期74-75,77,共3页
Acta Academiae Medicinae Jiangxi
关键词
川崎病
降钙素原
检测
儿童
kawasaki disease
procalcitonin
detection
children
