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小儿瑞芬太尼复合硝普钠控制性降压行全耳廓再造术的临床观察 被引量:1

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摘要 目的探讨瑞芬太尼复合硝普钠控制性降压,做小儿全耳廓再造Ⅱ期手术的可行性和安全性。方法择期行全耳廓再造Ⅱ期手术患儿30例,分为Ⅰ组(未降压组n=15)和Ⅱ组(降压组n=15)。在静吸复合全身麻醉下,手术开始前静脉微泵输注瑞芬太尼0.15-0.25μg/(kg·min),硝普钠1μg/(kg·min)开始,不超过3μg/(kg·min),使平均动脉压降至55~65mmHg,并维持此水平至手术结束加压包扎过程中,逐渐减量停药。术中监测心电图(ECG)、心率(HR)、有创平均动脉压(MBP)、脉搏氧饱和度(SpO2),术前、降压30min、术毕分别做血气分析和血乳酸浓度(lac),记录输液量、出血量、尿量。结果Ⅱ组降压后MBP与术前,术后及Ⅰ组相比有统计学差异(P<0.05),Ⅰ组、Ⅱ组HR变化无差异,Ⅱ组ECG均为窦性心律,Ⅱ组术中失血量明显少于Ⅰ组,P<0.05有统计学差异。降压30min,停止降压后血乳酸浓度改变无统计学差异(P>0.05)。结论瑞芬太尼复合硝普钠控制性降压可安全用于小儿全耳廓再造Ⅱ期手术,有效减少术中出血。
机构地区 昆明市儿童医院
出处 《中国实用医药》 2009年第34期145-147,共3页 China Practical Medicine
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