自体带角膜缘干细胞结膜瓣移植治疗假性胬肉

Clinical effect observation of conjunctival flap autograft and with corneal limbus stem cells autograft for treating traumatic pterygium

目的观察取自健眼的自体带角膜缘干细胞的结膜瓣移植治疗外伤后发生的假性胬肉的临床效果。方法对26例（26眼）假性胬肉应用取自健眼的带角膜缘干细胞的结膜瓣移植治疗，术后随访4～12月，对临床资料进行回顾性分析。主要观察指标：术后植片、角膜上皮愈合、胬肉复发及供区创面修复情况。结果所有患眼术后植片水肿3～5d后减轻，7～15d完全消退，拆线后植片血供良好，角膜上皮愈合。仅1例（3．85％）术后13d植片溶解脱落，1月后行2次手术植片成活。3例（11．54％）术后复发；健眼供区创面均恢复良好，均在7d后愈合，1月后充血消退，未影响外观。结论取自健眼的自体带角膜缘干细胞的结膜瓣移植治疗外伤后假性胬肉，术后复发率低，外观良好。

Objective To observe the clinical effect of conjunctival flapwith corneal limbus stem cells autograft for treating traumatic pterygium. Methods Date of 26 patients （26 eyes ） with traumatic pterygium originated by different ocular trauma who were treated with conjunctival flap autograft and with corneal limbus stem cells autograft. The date was evaluated retrospectively. The patients were followed for 4 - 12 months. Main outcome measures： Healing of the implants and corneal epithelium, recurrence and res- toration of the donor site. Results The implant was desquamate and lysed 13 days later in one eye （3.85%）. And the reoperation was successful after one month. Corneal epithelium was healing 7 - 15 days later. Three eyes （11.54%） were recurrened. The donor site surface was healing 7days later, and engorgement was dismissed one month later. There was no influence to external appearance. Conclusion Conjunctival flap with corneal limbus stem cells autograft is successful intreating traumatic pterygium.