抗青光眼药物对滤过手术疗效的影响

Effects of antiglaucoma medicines on the result of filtration surgery

目的探讨长期使用抗青光眼药物对滤过手术疗效的影响。方法将随机选择的115例138只眼滤过性手术后分为术前长期使用抗青光眼药物组与未使用组；术后分为使用噻吗心安组与未使用组，用Kaplan—Meier法分别作其两组的成功率分析。结果经X2检验前者无显著性意义（P＞0.05），后者有显著性意义（P＜0．05）。结论长期使用噻吗心安对滤过手术疗效有一定影响。

Objective To analize the effects of long term medical therapy on the outcome of filtration surgery.Methods 138 eyes of 115 patients were treated with filtration surgeries were randomly chosen and divided into two groups: one of those patients with long-term medical therapy or without medical therapy before the operation,the other of those paitents with postoperative topical timolol therapy or without the therapy. and both the two groups were included in the kaplan-Meier method.Results Preoperative use of medication did not influence the outcome of surgery (P>0. 05 ). Postoperative patients who did not have the topical timolol medication of filtration surgery had significantly belter success rates of filtration surgery (P<0. 05 ). Conclusion The topical timolol therapy has certain effects on the outcome of glaucoma filtration surgery.