肝性脑病的临床与MRI诊断

Clinical and MRI diagnosis in patients with acquired hepatocerebral degeneration

目的:研究获得性肝性脑部变性的MRI特征。方法:收集经临床确诊的获得性肝性脑部变性20例,其中男性13例,女性7例。全部病例均有完备的临床与MRI资料。结果:20例脑部均有阳性MRI表现,其中双侧、豆状核20例,苍白球17例,中脑红核周围15例,垂体前叶4例,表现为自旋回波(SE)序列T1WI为高信号,T2WI及FLAIR像无异常。结论:获得性肝性脑部变性的MRI征象具有特征性,MRI对该病的诊断有较高价值。

Objective To study the MR features in patients with acquired hepatocerebral degeneration. Method Total 20 patients （male 13 and female 7） with acquired hepatocerebral degeneration were examined by MRI. Results There were abnormal MRI manifestations in all of the 20 cases with acquired hepatocerebral degeneration.in which T1WI demonstrated increased signal in hibateral lentiform nucleus （ n = 20） , globus pallidus （ n = 17 ） , surrounding mesenccphalon red nucleus （ n = 15 ） , and in anterior pituitary （ n = 4 ）. While T2WI demonstrated no corresponding alteration in signal intensity. Conclusion Abnormal MR signal in the patients with acquired hepatocerebral degeneration has special features and MRI has right value for the diagnosis of this disease.