摘要
目的观察雷贝拉唑联合莫沙必利治疗返流性食管炎的临床疗效。方法68例返流性食管炎患者采用随机方法分成两组,每组34例;Ⅰ组应用雷贝拉唑联合枸橼酸莫沙必利;Ⅱ组单用雷贝拉唑,评价其临床疗效。结果68例返流性食管炎患者完成4周治疗,Ⅰ组、Ⅱ组症状缓解总有效率分别为94.1%(32/34),70.6%(24/34);Ⅰ组总有效率优于Ⅱ组(P<0.05)。内镜下缓解情况,Ⅰ组、Ⅱ组有效率分别为90%(18/20)、53.3%(8/15);Ⅰ组有效率优于Ⅱ组(P<0.05)。结论雷贝拉唑联合枸橼酸莫沙必利治疗返流性食管炎临床改善迅速,临床疗效优于单用雷贝拉唑。
Objective To observation the efficacy of rabeprazole and mosapride in the treatment of reflux esophagitis （RE）. Methods 68 cases of RE was randomized to 2 groups ： group Ⅰ ,group Ⅱ with 34 cases in each group. Groups Ⅰ were treated with rabeprazole and mosapride;groups Ⅱ were treated with rabeprazole single. Results 68 cases of RE were treated for 4 weeks. The total effective rate were 94. 1% （32/34） ,70. 6% （24/34）. Group Ⅰ was higher than group Ⅱ（ P〈0. 05 ）. The healing rate of esophageal mucosal lesion in group Ⅰ was higher than that of group Ⅱ（ P〈0. 05）. Conclusion The efficacy of rabeprazole and mosapride in the treatment of RE is better than that of rabeprazole single.
出处
《四川医学》
CAS
2009年第11期1747-1748,共2页
Sichuan Medical Journal
