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三苯氧胺对Survivin基因的作用及其机制 被引量：1

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摘要 三苯氧胺（TAM）是乳腺癌内分泌治疗的一线药物，近年来学者发现TAM可以通过诱导凋亡作用，从而杀伤乳腺癌细胞。Survivin是一种新型凋亡抑制因子，它广泛表达于胚胎、胎儿组织，及大多数常见的肿瘤组织。本实验旨在观察Survivin在TAM所诱导的乳腺癌细胞凋亡过程中所起的作用，并探讨其机制。
作者 宋文哲 宋燕 谭岩 方艳秋
机构地区 徐州医学院附属医院普通外科 吉林大学中日联谊医院基本外科 吉林大学第一医院中心研究室
出处 《中华实验外科杂志》 CAS CSCD 北大核心 2009年第12期1765-1765,共1页 Chinese Journal of Experimental Surgery
关键词 SURVIVIN基因 三苯氧胺 乳腺癌细胞 诱导凋亡作用 凋亡抑制因子 内分泌治疗 癌细胞凋亡 一线药物
分类号 R737.9 [医药卫生—肿瘤]
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共引文献22

同被引文献12

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中华实验外科杂志
2009年 第12期

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