摘要
对起病4天以内入院的23例急性胰腺炎患者血中3种细胞因子即TNF、IL1和IL6的变化情况进行动态观察,并分析其变化规律,以探讨其在判断病情严重性和估计预后中的价值。结果显示:所有患者血中3种细胞因子均升高,入院第1天轻、重症组TNF和IL1有显著差异,而IL6则在1周后才出现显著性差异。由此表明,在病程的不同阶段选择恰当的细胞因子指标有助于病情严重性的判断。细胞因子与急性胰腺炎多器官衰竭的关系尚需进一步探讨。
The serum activities of 3 cytokines (TNF,IL 1 and IL 6) were observed in 23 patients admitted within 4 days of onset of acute pancreatitis (AP). The results showed that the serum level of 3 cytokines raised in all of the AP patients, significant difference between TNF and IL 1 was abserved at admission and IL 6 did after one week of admission, suggesting that proper cytokine criteria are useful in predicting severity of the disease but the relationship between cytokines and MOF had not established.
出处
《中国普外基础与临床杂志》
CAS
1998年第6期350-351,共2页
Chinese Journal of Bases and Clinics In General Surgery
关键词
急性
胰腺炎
细胞因子
病情评估
多器官衰竭
Acute pancreatitis Cytokines Multiple organs failure Disease assessment