摘要
1例45岁男性糖尿病患者,因甲状腺功能亢进给予甲巯咪唑10mg,3次/d。1个月后,患者反复出现肌痛,每次持续1min。检测肌酸激酶(CK)为746U/L。停用甲巯咪唑2周后,肌痛消失,血CK水平恢复正常。再次口服该药,肌痛再次出现,遂停用。
A 45-year-old man with diabetes mellitus received thiamazole 10 mg thrice daily for hyperthyroidism. One month later,the patient experienced repeated episodes of muscular pain which lasted for one minute every time. His creatine kinase was 746 U/L. Thiamazole was stopped. Two weeks later,his symptoms disappeared and the creatine kinase level returned to within normal range. Myalgia recurred after readministration of thiamazole,then thiamazole was discontinued.
出处
《药物不良反应杂志》
2009年第5期367-368,共2页
Adverse Drug Reactions Journal
关键词
甲巯咪唑
不良反应
肌痛
肌酸激酶
thiamazole
adverse reactions
myalgia
creatine kinase
