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乙型肝炎病毒基因变异影响干扰素疗效的研究现状

Research status of hepatitis B virus genome variations influence on IFN-α therapeutic effect
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摘要 乙型肝炎病毒是一种高变异率的病毒,其特定位点的基因变异可以对干扰素-α的疗效起到抑制或促进作用。本文就乙型肝炎病毒基因变异对干扰素-α治疗慢性乙型肝炎疗效的影响进行扼要的阐述。 Hepatitis B virus had a high mutation rate, its site-specific genetic variation could inhibit or facilitate the effect of interferon-α. This article summarized the influence of hepatitis B virus genetic variations on IFN-α treatment of chronic hepatitis B.
出处 《世界感染杂志》 2009年第5期295-297,共3页 World Journal of Infection
基金 2008年福建医科大学科研项目资助课题(FZS08002) 2007年泉州市科技计划项目资助课题(2007Z15)
关键词 乙型肝炎病毒 基因变异 干扰素-Α Hepatitis B virus (HBV) gene mutation IFN-α
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二级参考文献12

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