期刊文献+

人体卵巢癌中砂粒体矿化的矿物学研究 被引量:4

Mineralogy of psammoma bodies in human ovarian cancer
下载PDF
导出
摘要 以卵巢浆液性癌中砂粒体矿化为研究对象,采用偏光显微镜、扫描电镜及其能谱、X射线粉晶衍射、傅立叶变换红外光谱和高分辨透射电子显微镜,对原位和分离处理样品的表面形貌、结构和矿物成分进行了观察测试。结果表明,卵巢浆液性癌中砂粒体具同心层状结构,矿化物质由纳米尺寸水草酸钙石和碳羟磷灰石两种物相组成,前者沉积在砂粒体内部,结晶度相对较高,后者沉积在砂粒体外层,结晶度差。 Ovarian cancer is one of the common malignant tumors in female reproductive organs. Psammoma bodies occurring in cell population is considered to be a phenomenon of ovarian serous carcer. In this paper,psammoma bodies from ovarian serous carcinomas were investigated by using SEM,EDAX,XRD,FTIR and HRTEM. The results show that the mineralized matter of the psammoma bodies with the concentric lamellated structure is composed of nano-size whewellite and carbonate hydroxylapatite. The former is deposited in the inner part of the psammoma body in a relatively high crystallinity,whereas the latter in the outer part in a low crystallinity.
出处 《岩石矿物学杂志》 CAS CSCD 北大核心 2009年第6期617-622,共6页 Acta Petrologica et Mineralogica
基金 国家自然科学基金资助项目(40872196)
关键词 卵巢癌 砂粒体 碳羟磷灰石 水草酸钙石 ovarian cancer psammoma body carbonate hydroxylapatite whewellite
  • 相关文献

参考文献3

二级参考文献26

  • 1杨若晨,鲁安怀,柳剑英,王长秋,张波.人体高发疾病的病理性矿物研究进展[J].矿物岩石地球化学通报,2006,25(4):395-402. 被引量:3
  • 2Han J, Daniel J C, Pappas G D. Expression of type IV collagen in psammoma bodies: inmlunofluoreseence studies on two fresh human meningiomas[J]. Acta Cytologica, 1996, 40 (2) : 177-181.
  • 3Kubota T, Yamashima T, Hasegawa M, et al. Formation of psammoma bodies in meningocytic whorls., ultrastructural study and analysis of calcified material[J]. Acta Neuropathologica, 1986, 70(3-4): 262-268.
  • 4Kirschvink J L, Kobayashikirschvink A, Woodford B J. Magnetite biomineralization in the human brain[J]. Proceedings of the National Academy of Sciences of the United States of America, 1992, 89(16) : 7683-7687.
  • 5Yang R C. Research of the characteristics of mineralization in several human epithelial tumors[D]. Beijing: Peking University, 2008(in Chinese).
  • 6Hunter G K. Interracial aspects of biomineralization[J]. Current Opinion in Solid State & Materials Science, 1996, 1(3) 430-435.
  • 7Rho J Y, Kuhn-Spearing L, Zioupos P. Mechanical properties and the hierarchical structure of bone[J]. Medical Engineering & Physics, 1998, 20(2) : 92-102.
  • 8Weiner S, Wagner H D. The material bone: structure mechanical function relations[J]. Annual Review of Materials Science, 1998, 28: 271-298.
  • 9Hugo V R, Juno D R, Donald R. Smith Psammoma booties in meningioma[J]. Virchows Archly, 1978, 380(4):317-325.
  • 10Ermel A E. Histogenesis of angiomatous areas in meningiomas.. an electron microscope study[J]. Pathology, 1974, 9:217-231.

共引文献23

同被引文献52

  • 1刘明娟,郭燕,张翎,黄兆民.卵巢癌的CT诊断与鉴别诊断[J].影像诊断与介入放射学,2007,16(2):67-71. 被引量:17
  • 2Das DK.Psammoma body:a product of dystrophic calcification or of a biologically active process that aims at limiting the growth and spread of tumor?[J].Diagn Cytopathol,2009;37(7):534-541.
  • 3Gonzalez JE,Caldwell RG,Valaitis J.Calcium oxalate crystals in the breast.Pathology and significance[J].Am J Surg Pathol,1991; 15(6):586-591.
  • 4Frappart L,Boudeulle M,Boumendil J,et al.Structure and composition of microcalcifications in benign and malignant lesions of the breast:study by light microscopy,transmission and scanning electron microscopy,microprobe analysis,and X-ray diffraction[J].Hum Pathol,1984; 15(9):880-889.
  • 5Lanyi M.Microcalcifications in the breast-a blessing or a curse? A critical review[J].Diagn Imaging Clin Med,1985;54(3-4):126-145.
  • 6Fandos-Morera A,Prats-Esteve M,Tura-Soteras JM,et al.Breast tumors:composition of microcalcifications[J].Radiology,1988; 169(2):325-327.
  • 7Fadare O,Chacho MS,Parkash V.Psammoma bodies in cervicovaginal smears:significance and practical implications for diagnostic cytopathology[J].Adv Anat Pathol,2004; 11(5):250-261.
  • 8Kubota T,Hirano A,Sato K,et al.Fine structure of psammorea bodies at the outer aspect of blood vessels in meningioma[J].Acta Neuropathol,1985; 66(2):163-166.
  • 9Johannessen JV,Sobrinho-Simoes M.The origin and significance of thyroid psammoma bodies[J].Lab Invest,1980; 43(3):287-296.
  • 10Cameron RI,McCluggage WG.Extensive psammomatous calcification of the uterus and cervix associated with a uterine serous carcinoma[J].J Clin Pathol,2004; 57(8):888-890.

引证文献4

二级引证文献10

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部