银杏达莫注射液治疗糖尿病肾病的临床观察

Influence of Ginkgo Leaf Extract and Dipyridamole Injection in Diabetic Nephropathy

目的观察银杏达莫注射液对糖尿病肾病患者24h尿微量清蛋白(U-Alb)的影响。方法将37例糖尿病肾病患者,随机分为治疗组20例,对照组17例,两组患者根据24h尿微量清蛋白分为A组(早期糖尿病肾病组),B组(临床糖尿病肾病组)。两组患者控制血糖、血压、血脂的治疗方法不变,治疗组加用静脉滴注银杏达莫注射液20ml,每日1次,连续14天,对照组不给上述治疗。结果治疗组:A组(早期。肾病组)与B组(临床肾病组)治疗后,24h尿微量清蛋白均较治疗前明显降低;与正常对照组相比明显降低,差异显著。结论银杏达莫注射可减少糖尿病肾病患者的尿蛋白。

Objective To study the influence of Ginkgo Leaf Extract and Dipyridamole Injection to urinary albumin （ U - Alb） in 24 hours in diabetic nephropathy. Methods 37 patients with diabetic nephropathy were involved in the study. They were divided into test group（20 patients） and control group（ 17 patients）. The test group was grouped into group A（ pristine diabetic nephropathy） and group B （clinical diabetic nephropathy） according to urinary albumin. The control group was grouped into group A （pristine diabetic nephropathy） and group B（ clinical diabetic nephropathy） according to urinary albumin. The test group was injected Ginkgo Leaf Extract and Dipyri- damole Injection 201xg from vein ,one time a day, 14 day continuously ,but control group without Ginkgo Leaf Extract and Dipyridamole In- jection. All patients were treated with same blood glucose, blood pressure, plasma lipids, and others. Results After the treatment of two groups, the level of the urinary albumin deceased obviously as compared with before treatment, and deceased significantly as compared with control group. Conclusion Ginkgo Leaf Extract and Dipyridamole Injection can lower urinary albumin in patients with diabetic ne- phropathy.