青年急性耳鸣高刺激率ABR的检测及临床意义

High stimulus rate auditory brainstem responses in young patients with acute tinnitus

目的研究高刺激率听觉脑干反应(Auditory brainstem response,ABR)检测对青年急性耳鸣的临床意义。方法选取青年急性耳鸣58耳与正常青年44耳,分别进行高、低刺激率ABR检测,比较波Ⅰ、Ⅲ、Ⅴ的潜伏期(peaklatency,PL)和Ⅰ～Ⅲ、Ⅲ～Ⅴ和Ⅰ～Ⅴ峰间潜伏期(interpeak latency,IPL)及两种刺激速率PL差值(ΔPL)、IPL差值(ΔIPL)。结果采用51.1次/s与11.1次/s的波PL及IPL的差值作为分析参数:耳鸣组波ⅠPL差值较正常组缩短,有统计学意义(P<0.05);Ⅰ～ⅤIPL差值较正常组延长,差异具有显著性(P<0.01)。正常组与耳鸣组高、低刺激率ABRⅠ～ⅤIPL差值>0.272ms的耳数分别为1耳和28耳。结论高刺激率ABR较常规ABR对青年急性耳鸣的检测更为敏感,可作为耳鸣患者的一种临床检查方法。

Objective To study characteristics of high stimulus rate auditory brainstem responses （ABRs） in young patients with acute tinnitus and their potential clinical significance. Methods Fifty eight ears with acute tinnitus were tested and compared with 44 normal ears. Results In tinnitus ears,the waveⅠlatency was shorter and Ⅰ-Ⅴ interval longer as compared to normal ears （p0.05 and p0.01 respectively）. Twenty eight ears in the tinnitus group demonstrated a 0.272 ms difference in Ⅰ-Ⅴ interval between low and high stimulus rate ABRs,compared to only 1 ear in the normal group. Conclusion High stimulus rate ABRs appear to be more sensitive in detecting abnormalities in young patients with acute tinnitus than routine ABR test.