摘要
目的探讨妊娠肝内胆汁淤积症(ICP)胎儿总胆汁酸浓度及对其胎儿生长发育的影响。方法选择ICP患者30例作为研究组、正常妊娠孕妇30例作为对照组。采用循环酶法测定两组胎儿脐动脉血清总胆汁酸(TBA)水平;新生儿均于生后15min内进行体重、身长的测量,计算新生儿庞代络指数(PI)。结果研究组脐动脉血胆汁酸高于对照组(P<0.05);新生儿体重及身长均明显低于对照组(P<0.01);PI明显高于对照组(P<0.01)。结论ICP胎儿生长发育异常,总胆汁酸升高可能是原因之一。
Objective To investigate the influence of intrahepatic cholestasis in pregnancy on fetal growth and development. Methods The total bile acid（TBA ）level was measured in 30 fetuses of intrahepatic cholestasis in pregnancy（case group）and 30 fetuses of normal pregnancy （control group）after elective cesarean section. The neonatal weight,length and Ponderal index were measured within 15 minutes after parturition. Results The TBA level in the case group was obviously higher than that of the control group. The neonatal weight was significantly lower and the length was significantly shorter in case group compared with the control group,while the Ponderal index of the case group was significantly higher than that of the control group. Conclusion The fetal growth and development are abnormal in intrahepatic cholestasis in pregnancy,and one of the reasons may be an increased TBA level.
出处
《中国现代医生》
2009年第33期42-43,共2页
China Modern Doctor
