改良翼状胬肉切除联合术中应用丝裂霉素C治疗初发性翼状胬肉的临床分析

Clinical analysis on primary pterygium treated by improved pterygium excision with mitomycin-C

目的观察改良翼状胬肉切除联合术中应用丝裂霉素C治疗初发性翼状胬肉的效果,探讨治疗初发性翼状胬肉的临床实用手术技巧。方法将131眼初发性翼状胬肉随机分为A组(73眼):采用改良翼状胬肉切除联合术中使用丝裂霉素C治疗;B组(58眼):采用单纯翼状胬肉切除联合术中使用撕裂霉素C治疗。两组均由同一医生手术操作,术后随访观察1～2年。结果术后随访中A组术后表层角膜炎发生率较B组少(P<0.05)。翼状胬肉复发A组4眼,复发率为6.3%;B组10眼,复发率为17.2%,两组比较差异有统计学显著意义(P<0.05)。结论采用改良翼状胬肉切除联合术中应用丝裂霉素C治疗初发性翼状胬肉,疗效满意、复发率低、刺激症状轻、并发症少,值得推广。

Objective To observe the effect of primary pterygium treated by improved pterygium excision with mitomycin-C. Methods One hundred and thirty-one eyes were randomly divided into two groups. Seventy-three eyes were treated by improved pterygium excision with mitomycin-C in group A, fifty-eight eyes were treated by simple pterygium excision with mitomycin-C in group B. All surgery had been done by the same doctor. The patients had been followed up for 1 - 2 years. Results The rate of complication in group A was lower than that in group B （ P 〈 0. 05）. The recurence rate was 6. 3% in group A（4 eyes）. The recurence rate was 17.2% in group B（ 10 eyes）. The diferences were statistical significance between two groups（P 〈0.05）. Conclusion The method of improved pterygium excision with mitomycin-C can decrease the recurence rate and complication. It is a simple method of pterygium surgery.