健康教育对外阴阴道假丝酵母菌病治疗的影响

Influence of health education on therapeutic effect for vulvovaginal candidiasis

目的探讨健康教育对外阴阴道假丝酵母菌病治疗效果的影响。方法将研究对象随机分为观察组和对照组，两组均使用硝酸咪康唑栓200mg每晚置入阴道，连用7天。观察组57例，由专人有针对性地对其进行外阴阴道假丝酵母菌病相关知识的健康教育，并发放宣教资料；对照组55例，仅告知其随访时间。停药后7—10天、4—5周分别进行随访，观察两组的治疗效果、复发率和用药依从性。结果第1次随访，观察组与对照组治疗有效率比较差异无统计学意义（χ^2=1．475，P=0．225）；第2次随访，观察组治疗有效率显著高于对照组（χ^2=4．253，P=0．039），用药依从性亦显著高于对照组（χ^2=13．581，P=0．000），两组复发率比较差异无统计学意义（χ^2=1．185，P=0．178）。结论健康教育能显著提高外阴阴道假丝酵母菌病患者的用药依从性和治疗效果。

Objective To investigate influence of health education on therapeutic effect for vulvovaginal candidasis （VVC）. Methods 112 women with VVC were divided into two groups randomly： observation group and control group. All patients were treated with vaginal placement of miconazole nitrate suppository at night for consecutive 7 days. In addition, all 57 women in the observation group were educated with health knowledge about VVC and spreaded health education materials by special persons, while 55 women in the control group was told the follow-up time only. At respective 7 - 10 days and 4 - 5 weeks after withdrawal of the drug, all the patients were followed up. The therapeutic effects, relapse rates and compliance of the patients in the two groups were observed and compared. Results At the first follow-up, there was no significant difference between the two groups in therapeutic effect （X2 = 1. 475, P = 0. 225）. At the second follow-up, in the observation group the therapeutic effect was more significant than that in the control group （χ^2 = 4. 253, P =0. 039） and the compliance of the patients was significantly better than the control group （χ^2 = 13. 581, P = 0. 000）. But there was no significant difference between the two groups in relapse rate （χ^2 = 1. 185, P = 0. 178 ）. Conclusion Health education can significantly improve compliance and therapeutic effect of the patients with VVC.