广州市白云区2044例健康人群麻疹抗体水平检测

Analysis of the measles antibody level among healthy group of population of 2044 in Baiyun District of Guangzhou

目的了解广州市白云区不同人群麻疹抗体水平，为防治工作提供参考依据。方法采用ELISA法对采集的2044例健康人群血清进行麻疹抗体检测，并对结果进行分析。结果健康人群麻疹IgG抗体阳性率和GMT水平分别为74．90％和1499，13岁组的抗体水平最低，抗体阳性率和几何平均滴度（GMT）分别为64．06％和1：545；其次为10～15岁组和0—1岁组，抗体阳性率和GMT分别为70．82％、1：456和71．6％、1：522；不同年龄组及不同医院抗体阳性率差异有显著性。结论广州市白云区健康人群对麻疹有一定的免疫力，近期不会发生大面积的麻疹流行，但是应重视麻疹的预防与控制，建议对1-3人群进行麻疹疫苗的加强免疫，提高抗体水平。

Objective To understand the antibody level of measles among various groups of people so as to provide scientific basis for outlining measures of prevention and treatment in Baiyun Distract of Guangzhou. Methods Serum samples were collected randomly from the group of healthy people to test measles-antibody with ELISA method. Results It showed the total measles-antibody positive rate and GMT of the group of healthy people were respectively 74. 90% and 1 ： 499. The lowest antibody level of the tested group was that of the people between 1 and 3 years old, whose measles-antibody positive rate and GMT were respectively 64. 06% and 1 ： 545. The second lowest antibody level was that of people between 10 and 15 years old and younger than 1 year old, whose positive rates were 70. 82% and 71.64% respectively and GMT were 1：456 and l： 522 respec- tively. There were statistical differences of measles-antibody in different age groups and among various hospitals. Conclusion An epidemic of measles could not occur in recent years in Baiyun Distract of Guangzhou. But we must intensify the prevention and control of measles. It is recommended that reinforced immunization of measles for 1- 3 year group should be taken seriously, for the enhancement of their antibody level.