2,5-二叔丁基-1,4-二(对苯甲酸氧基)苯的合成与表征

Synthesis and Characterization of 2,5-Di-tert-butyl-1,4-di-(p-benzoic acid oxyl) benzene

4-氟苯腈和2,5-二叔丁基对苯二酚亲核取代反应合成2,5-二叔丁基-1,4-二(对苯腈氧基)苯(产率87.00%,白色晶体,mp 280℃),将二腈在碱性条件下水解,合成了分子中同时含有2个醚键和2个叔丁基的芳香族二酸——2,5-二叔丁基-1,4-二(对苯甲酸氧基)苯(产率72.78%,白色针状晶体,mp>340℃)。产物经元素分析和IR1、H NMR、13C NMR和MS波谱表征确证。

2,5-Di-tert-butyl 1,4-di-（p-phenylene nitriles oxyl） benzene was synthesized via nucleophilic substitution reaction of 4-fluorobenzonitrile with 2,5-di-tert-butyl-p-dihydroxybenzene（yield 87.00%,white crystals,mp 280 ℃）.Then 2,5-di-tert-butyl-1,4-di-（p-benzoic acid oxyl） benzene with two ether bonds and two tert-butyls was obtained by alkaline hydrolysis of 2,5-di-tert-butyl 1,4-di-（p-phenylene nitriles oxyl） benzene（yield 72.78%,white acicular crystals,mp340 ℃）.The chemical structure of this product was confirmed by means of elemental analysis,IR,1H NMR,13C NMR and MS.