血小板参数与肝硬化患者Child—Pugh分级的关系

Detection of thrombocyte parameter in patients with hepatocirrhosis and it＇ s clinical significance

目的分析血小板参数与肝硬化Child—Pugh分级的关系，并探讨其临床意义。方法用ADVIA2120检测122例肝硬化患者的血小板计数（PLT）、血小板平均体积（MPV）及血小板压积（PCT），并与肝功能分级（Child—Pugh分级）比较。结果肝硬化组PLT、MPV、PCT较对照组均显著降低（P〈0．05），随着Child—Pugh积分增加，血小板P肌、MPV逐渐下降。C级组PCT比A，B级两组显著减低。结论血小板参数能间接反映血小板的功能．是评估肝硬化患者肝损坏程度的重要指标．对临床治疗、预后也有着重要的指导作用。

Objective To investigate the relationship between the thrombocyte parameters and hepatocirrhosis, and study the clinical significance. Methods Thrombocyte parameters of 122 patients with hepatocirrhosis was detected by ADVIA 2120;The patients with hepatocirrhosis were classified with Child -Pugh grades and they were compared with thrombocyte parameters. Results The values of thrombocyte parameters in patients with hepatocirrhosis were significantly lower than the health physical examination,and the values of PLT and MPV descreased with the increase of the Child - Pugh grades. Conclusions Thrombocyte parameters can indirectly reflect function of platelet. The thrombocyte parameters are important indices for evaluating the damage degree of live in patients with hepatocirrhosis, guiding clinical therapy and estimating prognosis.