^99mTc—MIBI双时相显像定位诊断原发性甲状旁腺功能亢进的临床价值

Clinical value of the localization of primary hyperparathyroidism with double phase ^99mTc - MIBI imaging

目的探讨放射性核素^99mTc—MIBI双时相显像在原发性甲状旁腺功能亢进患者术前诊断、定位的应用价值。方法2003年3月至2008年3月，对9例原发性甲状旁腺功能亢进患者术前行^99mTc—MIBI双时相核素显像，切除后冰冻切片病理检查明确诊断，并对其疗效进行随访。结果9例均手术，共发现10个甲状旁腺病灶，病理检查证实甲状旁腺腺瘤8例，甲状旁腺瘤伴甲状旁腺增生1例。所有患者恢复良好，无并发症出现，随访1～5年，临床症状无复发，疗效满意。结论原发性甲状旁腺功能亢进双时相核素显像可明确甲状旁腺瘤的诊断及便于手术定位。

Objective To investigate the appliance value of ^99mTc -MIBI parathyroid imaging in the diagnosis and localization of primary hyperparathyroidism. Methods Nine patients with primary hyperparathyroidism were made radionuelide delay image by ^99mTc - MIBI. Frozen section pathological examination was used to determine the diagnosis post parathyroidoma excision. Results Ten leision tissues were found in these patients, 8 cases of them were parathyroidoma, and 1 case was parathyroidoma company with parathyroid hyperplasia. All patients got a better prognosis, no complication had been found in all of them. Follow up from 1 to 5 years, the clinic symptom of hyperparathyroidism had no recurrence in these patients of this group, and satisfying effect had been acquired. Conclusions Parathyroiddelay image of ^99mTc - MIBI could accurately diagnose and make the location of primary parathyroidma so as to determine the place of parathyroidma during operation.