20例男性垂体催乳素瘤MRI特征分析并文献复习

Prelimilary study on MRI findings of prolactinomas in male

目的探讨男性垂体催乳素瘤的临床及MRI特征，提高其正确诊断率：方法回顾性分析20例经手术病理或内分泌治疗有效证实的男性催乳素腺瘤。结果在MRI诊断的20例男性催乳素瘤患者中，微腺瘤9例，大腺瘤11例。平扫T1WI呈稍低或等信号，T2WI均为稍高～高信号，常规增强均可见明显强化。侵袭性者均为大腺瘤，多伴有视交叉受侵或蝶窦、海绵窦侵犯，部分伴骨质破坏；结论男性垂体催乳素瘤的临床与MRI表现均与女性不同，MRI对催乳素瘤诊断有重要价值，但应注意临床与影像两者结合，以达到早期、准确诊断。

Objective To investigate the clinicai characteristics and MR1 findings of pituitary prolactinomas in male and to improve the diagnostic accuracy of the disease. Methods Retrospectively study the MR1 findings of 20 prolactinomas already verified by either pathology or medical treatment. Results Of all 20 cases, 9 cases were proved with microadenomas and 11 with macroadenomas. Prolactinomas showed low or isointense on TIWI, slightly high or hyperintense on T2WI. Obvious enhance could be seen ＇after con- trast medium administration. All invasivc cases were macroadenomas, with the involvement of stalk hypophy- sial,cavernous sinus sphenoidal sinus or even skull base. Conclusion Prolactinomas in male are different with those in female both clinically and in MRI findings. MRI is useful in diagnosing prolactinomas, but we should also pay attention to the clinical data in order to reach early and accurate diagnosis.