脑脊液囊虫抗体检测与细胞学检查对比分析诊断脑囊虫病的价值

Contract Analysis on Cysticercus Antibody Detection Andccytological Examin Cerebraspinal Fluid for Diagnosis of Cerebral Cysticercosis

应用ＡＢＣ—ＥＬＩＳＡ、ＳＰＡ—ＥＬＩＳＡ和细胞学检查４１例脑囊虫病患者脑脊液抗囊虫抗体及细胞学异常者进行对比观察分析。结果显示，ＡＢＣ—ＥＬＩＳＡ法阳性３７例（９０．２％），ＳＰＡ—ＥＬＩＳＡ法阳性３４例（８０．５％），细胞学异常者２９例（７０．７％）。３７例脑脊液抗囊虫抗体阳性者嗜酸性粒细胞、激活淋巴细胞、浆细胞、嗜碱性粒细胞的检出率分别为７８．３％、７３．０％、７５．７％和２４．３％；抗体滴度１∶３２０时各类病理性细胞数达到最高值分别占５６．８％、６４．９％、６７．６％和１８．９％与非囊虫病和非中枢神经系统疾病有显著性差异（Ｐ＜０．０１）。免疫学检测与细胞学检查互相配合更有利于对本病的诊断。

In this paper the contract analysis of cysticercus antibody and cytological abnormal in cerebrospinal fluid (CSF) of 41 cerebral-cysticercosis patients by ABC-ELISA, SPA-ELISA and cellular stain is reported. The result showed that with ABC-ELISA 37 cases of antibody positive were found (90 2%), while with SPA-ELISA 34 cases found (80 5%) and 29 cases of cellular abnormal (70 7%) detected. In 37 cysticercus antibody positive patients the detected ratesoof eosinophils, actived lymphoidocytes, plasmacyte, basophils were found to be 78 3%, 73 0%, 75 7%, and 24 3% respectively. When antibody titers reached the highest 1∶320 the proportion of the above pathological cells showed to be 56 8%, 64 9%, 67 6% and 18 9% respectively. With non-cerebral cysticercosis and non-center nervous diserses there was a signilicant difference (P<0 01). The combination of immunological and cytological exams more advantageaus to the diagnosis of cerebral cysticercosis.