^(99m)Tc-MIBI提前显像在心肌梗塞诊断中的应用

Application of Early Imaging Using ^(99m)To-MIBI SPECT in Myocardial infarction

目的：探讨99mTc-MIBI心肌显像能否成为急性心肌梗塞的快速诊断手段。资料和方法：选择临床确诊的心肌梗塞患者35例，于注射99mTc－MIBI后10min与60min以相同条件分别进行SPECT显像，并以相同条件分析处理图像，记录心肝肺的放射性计数率，比较两次显像结果的差异。结果；10min像阳性率31.2％，60min像为308％，符合率95.2％。有22个节段（4．8％）两次显像缺损程度有差异，以下后壁居多（13／22.59.1％）。图像质量以60min像为佳，心脏计数率随时间延长而降低，而心肝比、心肺比升高。结论：10min显像与60min显像在本组病例中具有很好的诊断一致性，至少可为急性心梗提前50min提供诊断，可望成为急性心梗的一种快速诊断手段。

Purpose:To detect the feasibility of 99mTc-MIBI early imaging as a quick diagnostic method for acute myocardial infarction.Materials and Methods:35 patients with known myocardial infarction were studied early. SPECT myocardial imaging was undertaken at10minutes after intravenous injection of 99mTc-MIBI and repeated imaging at 60minutes as control. Results: The diagnostic sensitivity areboth 100 % at the two imaging phases. In 455 segments of the 35 patients, 142 segments (31. 2 % ) were found positive at 10M-imaging.The myocardial radioactivity in 60M-imaging was lower but the ratios between myocardial and hepatic radioactivity and myocardial and pulmonary radioactivity were higher(P < 0. 001 ). Conclusion: The diagnostic agreement between 99mTc-MIBI myocardial imaging at early(10min) and at routine (60min) was good in this group of patients. 10M-imaging could provide diagnostic imformation early, and might become a quick diagnosis method for acute myocardial infarction.