大肠癌病人术后复发Cox模型多因素分析

Multifactorial Analyses on Recurrence of Colorectal Carcinoma

应用Cox回归模型分析方法,对364例术后大肠癌患者进行肿瘤复发因素分析.结果显示,单因素分析有侵犯周径、大体类型、Dukes分期、术后转移、B血型和浸润深度等7个因素有显著性意义(P<0.05).Cox模型多因素分析有Dukes分期、B血型、浸润深度、大体类型及侵犯周径依次进入模型,相对危险度(RR)分别为1.57、0.57、1.28、2.16、1.23.并对其复发因素进行了讨论.

364 cases of colorectal carcinoma underwent surgical ablation. Cox's proportional hazards regression model was used to investigate the factors influencing tumor recurrence. The result showed that 7 factors were associated with the recurrence rate of colorectal carcinoma in the univalent analyses. The multilent analyses of Cox's model demonstrated that Dukes stage,blood group B,depth of penetration.histological type and invadea periphery were the factors influencing the tumor recurrence of colorectal carcinoma .and the relative risk(RR)was 1. 57.0. 57,1. 28,2. 16 and 1.23 respectively. The factors influencing tumor recurrence were discussed.