93例胃肠道间质瘤的诊断和治疗
Diagnosis and Treatment of 93 Cases of Gastrointestinal Stromal Tumors
摘要
对93例胃肠道间质瘤患者的临床诊断和特点、病理特点、治疗方法及预后情况等进行回顾性分析。病理及免疫组织化学检查有助于诊断。治疗方法首选是手术切除,不主张常规行标准淋巴结清扫,但术后转移复发率高,其预后与危险性评分及发病部位有关;对于转移或不能切除者,Glivec是目前最有效的系统治疗方法。
出处
《现代诊断与治疗》
CAS
2009年第6期364-365,共2页
Modern Diagnosis and Treatment
参考文献10
-
1Fletcher CD, Berman JJ, Corless C, et al. Diagnosis of gastroin test inalstromal tumors: a consensus approach [ J ]. Hum Pathol, 2002,33 ( 5 ) : 459-465.
-
2Mazur MT. Clark HB1 Gastric stromal tumors;reapp raisal of histogenesis [J]. Am J Surg Patho1,1983,7(6) :507.
-
3Hirota S, Isozadi K, Moriyama Y, et al. Gain of function mutation of c2kit in human gastrointestinal stromal tumors [ J ]. Science, 1998,279 ( 5350 ) : 577-580.
-
4Heinrich MC, Corless CL, Duensing A, et al. PDGFA activating mutations in gastrointestinal stromal tumors [J]. Science, 2003,299 ( 5607 ) : 708- 710.
-
5Miettinen M, Sobin L, Lasota J, et al. Evaluation of malignancy and prognosis of gastrointestinal stromal tumors : a review [ J ]. Hum Pathol, 2002, 33(5) :478.
-
6Lewin K J, Riddel RH, Weinstein WM, et al. Gastrointestinal pathology and its clinical imp lications [ M ]. New York: Igaku Shoin, 1992. 284- 341.
-
7Franquemont DW. Differentiation and risk assessment of gastrointestinal stromal tumors [ J ]. Am J Clin Pathol, 1995,103 ( 1 ) :41-47.
-
8Hassan I, You YN, Shyyan R, et al. Surgically managed gastrointestinal stromal tumors : a comparative and prognostic analysis [ J ]. Ann Surg Oncol ,2008,15 ( 1 ) :52-59.
-
9Bilimoria MM, Holtz DJ, Mirza NQ, et al. Tumor volume as aprognostic factor for sarcomatosis [ J ]. Cancer, 2002,94 ( 9 ) :2441.
-
10Joensuu H, Roberts PJ, Sarlomo-Rikala M, et al. Effect of the tyrosine kinase inhibitor STI571 in a patient with metastatic gastrointestinal stromal tumor[ J]. N Engl J Med ,2001,344(14) :1052-1056.
-
1李光,张海燕.胃肠道间质瘤89例临床分析[J].实用癌症杂志,2008,23(3):273-275. 被引量:2
-
2田红,陈捷,吴颖,李莉莉.伊马替尼治疗加速期和急变期慢性髓细胞性白血病的临床研究[J].第二军医大学学报,2007,28(8):928-928. 被引量:2
-
3陈远崇,王今,张忠涛.32例胃肠道间质瘤的临床分析[J].医学动物防制,2004,20(11):713-715.
-
4丁家华,孙耘玉,高冲,陈宝安.慢性粒细胞性白血病慢性期10年以上者三例特征分析[J].江苏医药,2002,28(6):478-478.
-
505056 Novartia寻求对Glivec的批准[J].国外药讯,2001(5):23-23.
-
6叶朕雄,汪昱,郭明高.胃肠道间质瘤诊治进展[J].山东医药,2007,47(8):78-79. 被引量:6
-
7王健民,侯军,许小平,楼敬伟,高磊,居小萍,宋献民,闵碧荷.格列卫治疗慢性粒细胞白血病疗效的初步分析[J].第二军医大学学报,2002,23(9):1039-1040. 被引量:1
-
8施桂兰(摘).11063 Novartis申请Glivec用于四种新的罕见癌症[J].国外药讯,2006(11):28-29.
-
9欧盟批准Glivec用于术后胃肠道间质瘤[J].健康大视野,2009(11):126-126.
-
10金伟秋.03036 Glivec可能是白血病的“突破”口[J].国外药讯,2001(3):19-20.