百合化学成分的分离和结构鉴定

STUDIES ON CHEMICAL CONSTITUENTS OF LILIUM BROWNII

从百合（ＬｉｌｉｕｍｂｒｏｗｎｉＦ．Ｅ．Ｂｒｏｗｎｖａｒ．ｖｉｒｉｄｕｌｕｍＢａｋｅｒ）的干燥肉质鳞片中分离得到５个化合物，根据光谱（ＩＲ，ＦＡＢＭＳ，１ＨＮＭＲ，１３ＣＮＭＲ，ＤＥＰＴ，ＨＭＱＣ，ＨＭＢＣ）解析和理化性质，分别鉴定为β谷甾醇（Ｉ）、胡萝卜苷（Ｉ）、正丁基βＤ吡喃果糖苷（ＩＩ）、２６ＯβＤ吡喃葡萄糖３β，２６二羟基５胆甾烯１６，２２二氧３ＯαＬ吡喃鼠李糖（１→２）βＤ吡喃葡萄糖苷（ＩＶ）、２６ＯβＤ吡喃葡萄糖３β，２６二羟基胆甾烷１６，２２二氧３ＯαＬ吡喃鼠李糖（１→２）βＤ吡喃葡萄糖苷（Ｖ）。其中ＩＶ和Ｖ为新化合物，Ｉ、Ｉ和ＩＩ为首次从该植物中分得。

Lilium brownii F.E.Brown var. viridulum Baker is a well known and very important traditional Chinese medicine. It has been used as sedative, antitussive, anti inflammatory or as a nutrient. Five compounds were isolated from the bulbs of Lilium brownii. On the basis of spectroscopic analysis (IR, FAB MS, 1HNMR, 13 CNMR, DEPT, HMQC, HMBC) and their physicochemical properties, they were identified as β sitosterol (I), daucosterol (II), n butyl β D fructopyranoside (III), 26 O β D glucopyranosyl 3β,26 dihydroxy 5 cholesten 16,22 dioxo 3 O α L rhamnopyranosyl (1→2) β D glucopyranoside (IV), 26 O β D glucopyranosyl 3β,26 dihydroxy cholestan 16,22 dioxo 3 O α L rhamnopyranosyl (1→2) β D glucopyranoside(V). Among them, I, II and III were isolated from this plant for the first time, IV and V are new compounds.