社区干预对2型糖尿病大血管病变的影响

Effect of Community Intervention on Macrovascular Complications in Patients with Type 2 Diabetes Mellitus

目的探讨社区干预对改善2型糖尿病大血管病变IMT、hs-CRP的效果。方法将180名患者随机分为干预组和对照组,每组各90人。对干预组入组患者社区干预2年以上,分别对两组患者测定IMT、hs-CRP、空腹血糖、血脂、肥胖指数(BMI)、HbA1c,进行对比。结果干预/对照2年后干预组患者IMT值及hs-CRP值与对照组相比差异均有统计学意义(P<0.01),两组干预/对照后HOMA-IR值、TC比较(P均<0.05),干预组FPG与对照组FPG比较差异有统计学意义(P<0.01)。两组各组数据干预/对照前后比较差异均有统计学意义(P<0.0001)。结论通过社区的规范化综合性干预和管理可以减轻糖尿病大血管病变的程度。

Objective To explore the effect of community intervention on improving MIT value and the level of hs - CRP in type 2 diabetes mellitus patients with macrovascular complications. Methods Altogether 180 patients were randomly divided into intervention group （n = 90） and treatment group （n = 90）. Aften twoyear community intervention, IMT, hs - CRP, FBG, TC, BMI, and HbAIC of the two groups were determined and the results were compared. Results After 2 - year intervention/treatment, there were statistically significant differences in IMT value and the level of hs - CRP between intervention group and treatment group （P〈 0.01）. There were statistically significant differences in the levels of HOMAIR value, TO, and FPG between intervention group and treatment group （P〈 0.0.5, P〈 0.05, P〈 0.01）. Before and after intervention/ treatment, each datum of the two groups had statistically significant differences （P〈 0. 0001 ）. Conclusions Through standardized comprehensive community intervention and management may reduce diabetes trunk pathological change＇s degree.