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CD4^+CD25^+Foxp3^+调节性T细胞在肿瘤免疫治疗中的研究进展

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摘要 调节性T细胞(regulatory T cell,Treg)是一群发挥免疫抑制功能的淋巴细胞,在维持机体内环境稳定、预防自身免疫病、控制移植排斥中发挥重要作用,但却抑制了机体的抗肿瘤免疫。最近几年,有关Treg作为肿瘤的免疫治疗的靶细胞研究很多,本综述总结了这些研究的新进展,分析通过抑制Treg进行肿瘤免疫治疗的各种手段以及存在的隐患。
作者 张通通 沈立松
机构地区 上海交通大学医学院附属新华医院检验科
出处 《现代免疫学》 CAS CSCD 北大核心 2009年第6期522-525,共4页 Current Immunology
基金 上海市科委基础研究重点基金资助项目(07JC14045)
关键词 TREG 肿瘤 免疫治疗
分类号 R730.3 [医药卫生—肿瘤]
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参考文献19

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共引文献19

现代免疫学
2009年 第6期

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