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单一靶控输注异丙酚不同血药浓度对体感诱发电位的影响 被引量：1

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摘要 目的研究单一靶控输注异丙酚不同的血药浓度对短潜伏期体感诱发电位(sensory evoked poten-tial,SEP)的影响。方法20例ASAⅠ～Ⅱ级,择期神经外科手术进行术中监测患者,术前SEP检查无异常,均未给予任何的术前药物,单一靶控输注异丙酚,当血浆药物浓度稳定在3、4、5μg/mL时记录患者P15、N20、P25波的潜伏期和P15-N20、N20-P25波幅的改变。结果P15、N20、P25波潜伏期随着异丙酚血药浓度的升高而延长,异丙酚血药浓度5μg/mL时,与清醒比较P15、N20、P25波潜伏期明显延长,与清醒比较N20-P25波幅明显升高。结论体感诱发电位是监测靶控输注异丙酚麻醉深度的较好指标。
作者 冯颖辰 高旻 韩如泉 刘淑玲
机构地区 首都医科大学附属北京天坛医院麻醉科 北京市神经外科研究所
出处 《广东医学》 CAS CSCD 北大核心 2009年第12期1882-1883,共2页 Guangdong Medical Journal
关键词 异丙酚 靶控输注 体感诱发电位 神经外科
分类号 R743.34 [医药卫生—神经病学与精神病学] R969.1 [医药卫生—药理学]
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  • 1隋大凯 岳云 等.催醒时定量脑电图界值预示唤醒的灵敏度及特异度研究[J].中华麻醉学杂志,1997,17:545-545.
  • 2[1]Billard V, Cazalaa JB, Servin F, Viviand X. Target-controlled intravenous anesthesia [J]. Ann Fr Anesth Reanim , 1997; 16(3): 250-273.
  • 3[2]Milne SE, Kenny GN. Futrue applications for TCI systems [J]. Anaesthesia , 1998; 53(Suppl 1): 56-60.
  • 4[3]Gale T, Leslie K, Klμger M. Propofol anaesthesia via target controlled infusion or manually controlled infusion: Effects on the bispectral index as a measure of anaesthetic depth [J]. Anaesth Intensive Care , 2001; 29(6):579-584.
  • 5[4]Hunt-Smith J, Donaghy A, Leslie K, Klμger M, Gunn K, Warwick N. Safety and efficacy of target controlled infusion (Diprifusor) vs manually controlled infusion of propofol for anaesthesia [J]. Anaesth Intensive Care , 1999;27(3):260-264.
  • 6[5]Russell D, Wilkes MP, Hunter SC, Glen JB, Hutton P, Kenny GN. Manual compared with target-controlled infusion of propofol [J]. Br J Anaesth , 1995;75(5):562-566.
  • 7[6]Zhao H, Chai W, Yang YH, Yin GW. Effect of propofol on artificial abortion [J]. Di-si Junyi Daxue Xuebao (J Fourth Mil Med Univ) , 2000; 21(6): S112.
  • 8[7]Struys M, Versichelen L, Thas O, Herregods L, Rolly G. Comparison of computer controlled administration of propofol with two manually controlled infusion techniques [J]. Anaesthesia , 1997;52(1):41-50.
  • 9[8]Servin FS. TCI compared with manually controlled infusion of propofol: A multicentre study [J]. Anaesthesia , 1998;53(Suppl 1):82-86.
  • 10[9]Olmos M, Ballester JA, Vidarte MA, Elizalde J, Land Escobar A. The combined effect of age and premedication on the propofol requirements for induction by target-controlled infusion [J]. Anesth Analg , 2000;90(5):1157-1161.

共引文献25

同被引文献14

  • 1杨涛,彭书崚,曹铭辉,钟亮,李珏,夏淑轩,吴强.手术病人体感诱发电位、脑电双频谱指数与异丙酚血药浓度、异氟醚呼气末浓度的关系[J].中华麻醉学杂志,2005,25(6):460-461. 被引量：6
  • 2Banoub M, Tetzlaff JE, Schubert A. Pharmacologic and physio- logic influences affecting sensory evoked potentials. Anesthesiol- ogy, 2003, 99:716-737.
  • 3Boisseau N, Madany M, Staccini P, et al. Comparison of the effects of sevoflurane and propofol on cortical somatosensory evoked potentials. Br J Anaesth, 2002,88 : 785-789.
  • 4Angel A. Central neuronal pathways and the process of anaes- thesia. BrJ Anaesth, 1993,71:148-163.
  • 5Kubota T, Hirota K, Yoshida H, et al. Effects of sedatives on noradrenaline release from the medial prefrontal cortex in rats. Psyehopharmaeo (Berl), 1999,146 : 335-338.
  • 6Angel A. Thalamus, neural meehanisms of anesthesia. New Jersey: Humana Press Inc, 2003. 125-148.
  • 7Shirasaka T, Yonaha T, Onizuka S, et al. Effects of orexin-A on propofol anesthesia in rats. J Anesth, 2011,25 (1) : 65-71.
  • 8Kushikata T, Hirota K, Yoshida H, etal. Alpha-2 adrenoeeptor activity affects propofol-induced sleep time. Anesth Analg, 2002, 94(5) : 1201-1206.
  • 9Jorm CM, Stamford JA. Actions of the hypnotic anaesthetic, dexmedetomidine, on noradrenaline release and cell firing in rat locus eoeruleus slices. Br J Anaesth, 1993, 71:447-449.
  • 10J Hirota K, Kudo M, Kudo T, et al. Inhibitory effects of intra- venous anaesthetic agents on K+-evoked norepinephrine and do- pamine release from rat striatal slices: possible involvement of P/ Q-type voltage-sensitive Ca2+ channels. Br J Anaesth, 2000,85 (6) :874-880.

引证文献1

广东医学
2009年 第12期

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