发热待查1854例临床分析

Analysis on 1854 cases with fever of unkown origin

目的分析发热待查患者的临床资料及病因构成与地区的关系。方法回顾性总结近10年来我国1854例发热待查的临床资料,对其年龄、病因、病种与地方的关系等进行比较。结果感染性疾病、自身免疫性疾病和恶性肿瘤患者为发热待查的主要原因,占总病例的89.05%,其中感染性疾病仍为主要病因(62.72%),自身免疫性疾病(14.89%)、肿瘤(11.43%)分别列居第二、三位。其中,感染性疾病当中结核与伤寒的发病率有一定地区差异。结论不明原因发热涉及的病因众多,发病机制复杂,临床工作中其具体原因还有待于进一步探讨。

Objective To analyse the clinical data of fever of unknown origin （FUO） and the relationship of the etiology in different area. Methods All 1854 cases with fever of unknown origin in the past 10 years reported in China were reviewed retrospectively and the age, pathogenic, kinds of diseases were compared in different areas. Results Infectious diseases, autoimmune diseases and malignancy tumor were the major cause of FUO, accounting for 89.05% in the total cases, of which infectious disease was the main cause （62.72%） , the second was autoimmune disease （ 14.89% ） , the third was cancer （ 11.43% ）. The incidence of tuberculosis and typhoid fever were obviously different between various places. Conclusions The cause of fever of unknown origin involved in numerous complex pathogenesis which need to be further ex- plored in clinical trials.