两种不同类型的气管支架置放后安全性评价

Clinical evaluation on safety of stenting implantment in treatment of airway stenosis with two different type stents

目的 探讨不锈钢Z型支架和镍钛合金网状支架治疗气道狭窄病变远期安全性。方法不锈钢Z型支架组33例，镍钛合金网状支架组31例，分别于放置后3个月、6个月和9个月行内镜检查，记录肉芽肿发生情况及程度。结果两组患者均有不同程度的肉芽组织增生，Z型支架组肉芽肿增生程度低于镍钛合金网状支架组。结论不锈钢Z型支架和镍钛合金网状支架肉芽肿发生率是有区别的，Z型支架适合良性狭窄的治疗，网状支架适合恶性病变的治疗。

Objective To evaluate the long-term safety of stenting therapy in the treatment of airway stenosis with stainless steel Z-stent and nitinol mesh stent. Methods Thirty-three cases were treated with stainless steel Z-stent group,while other 31 cases treated with nitinol mesh stent. At the time of 3,6 and 9 months after stenting, bronchoscope were performed and the occurrence and extent of granuloma were recorded. Results Varying degrees of granulation tissue hyperplasia were all observed in two groups. The occurrence of granuloma in stainless steel Z-stent group was far less than nitinol mesh stent group. Conclusions The difference of occurrence of granulation tissue hyperplasia between stainless steel Z-stent group and granuloma nitinol mesh stent group are significant. Z-type stent is more suitable for the treatment of benign tracheobronchial stenosis, however, nitinol mesh stent is adaptive for malignant tracheobronchial stenosis.