多原发癌384例临床分析

Clinical analysis of 384 cases with multiple primary carcinoma

目的正确识别多原发癌(MPC)和探讨其治疗原则。方法经计算机病案检索系统从9278例消化道、肺和乳腺等癌症患者中查找MPC病例。结果共查出384例有病理证实的MPC病例,三病种的MPC总发生率为4.1%,其中消化道癌症患者中MPC的发生率为5.9%;肺癌为3.0%;乳腺癌为2.2%。结论MPC与转移癌或复发癌在治疗上有原则性区别,因为前者仍有机会争取根治性治疗;而后者往往仅为姑息性治疗,两者预后有所不同。

Objective To discuss the differential diagnosis and principle of of multiple primary carcinomas （MPC）. Methods Patients with MPC were selected from 9 278 cancer cases （including digestive tract cancer, lung cancer and breast cancer）. Results 384 patients with MPC were observed, and the overall incidence of MPC was 4.1%. The incidence of MPC in patients with digestive tract cancer, lung cancer and breast cancer were 5.9%, 3.0% and 2.2%, respectively. Conclusion There were differences in principle of recurrent cance.