摘要
用邻胺基酚或水扬酸为原料经三步反应制得中间体２，６－二氯苯并唑，用对苯二酚和２－氯丙酸经一步合成了另一中间体２－（４－羟基苯氧基）－丙酸乙酯，再使两个中间体在相转移催化剂催化下缩合得到除草剂２－（４－（６－氯－２－苯并唑氧基苯氧基）丙酸乙酯．全程收率为５１％．
In synthesis of the highly effective herbcide ethyl 2-[4-(6-chloro-2-benzoxazoloxy)] propionate, first, utilizing three and one reaction steps, the intermediate 2,6-dichlorbenzoxazole from o-amindphenoxy and urea or o-hydroxybenzoic acid and oxyammonia hydrochloride and the other intermediate ethyl 2-(4-hydroxyphenoxy)-propionate from para-dihydroxy-benzene and 2-chloropropionacid have been prepared, respectively. Then, the title compound has synthesized from the two intermediates in the presence of the phase transfer catalyst PEG. The total yield is 51%.
出处
《哈尔滨师范大学自然科学学报》
CAS
1998年第4期77-80,共4页
Natural Science Journal of Harbin Normal University
关键词
除草剂
合成
羟基苯氧基
丙酸乙酯
芳氧丙酸类
Synthesis
Herbcide
Ethyl 2-(4-hydroxyphenoxy)-propionate
2,6-dichlorobenzoxazole
