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5α还原酶抑制剂预防前列腺癌的若干问题 被引量:1

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摘要 众所周知二氢睾酮(DHT)对前列腺生长和发育及前列腺癌(PCa)的发生和发展起着十分重要的作用。5α还原酶抑制剂(5-ARI)阻止睾酮向DHT转化,使前列腺内DHT水平下降90%。20世纪90年代就有学者认为5-ARI可通过减少雄激素的刺激预防PCa。
作者 史时芳
出处 《中华泌尿外科杂志》 CAS CSCD 北大核心 2009年第12期860-863,共4页 Chinese Journal of Urology
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